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Article  |  2021-03-31

Development of a 50K SNP Array for Japanese Flounder and Its Application in Genomic Selection for Disease Resistance

Single nucleotide polymorphism (SNP) arrays are a powerful genotyping tool used in genetic research and genomic breeding programs. Japanese flounder (Paralichthys olivaceus) is an economically-important aquaculture flatfish in many countries. However, the lack of high-efficient genotyping tools has impeded the genomic breeding programs for Japanese flounder. We developed a 50K Japanese flounder SNP array, "Yuxin No. 1," and report its utility in genomic selection (GS) for disease resistance to bacterial pathogens. We screened more than 42.2 million SNPs from the whole-genome resequencing data of 1099 individuals and selected 48 697 SNPs that were evenly distributed across the genome to anchor the array with Affymetrix Axiom genotyping technology. Evaluation of the array performance with 168 fish showed that 74.7% of the loci were successfully genotyped with high call rates (> 98%) and that the polymorphic SNPs had good cluster separations. More than 85% of the SNPs were concordant with SNPs obtained from the whole-genome resequencing data. To validate "Yuxin No. 1" for GS, the arrayed genotyping data of 27 individuals from a candidate population and 931 individuals from a reference population were used to calculate the genomic estimated breeding values (GEBVs) for disease resistance to Edwardsiella tarda. There was a 21.2% relative increase in the accuracy of GEBV using the weighted genomic best linear unbiased prediction (wGBLUP), compared to traditional pedigree-based best linear unbiased prediction (ABLUP), suggesting good performance of the "Yuxin No. 1" SNP array for GS. In summary, we developed the "Yuxin No. 1" 50K SNP array, which provides a useful platform for high-quality genotyping that may be beneficial to the genomic selective breeding of Japanese flounder.

Qian Zhou ,   Ya-dong Chen   et al.

Review  |  2021-03-31

Fundamentals and Processes of Fluid Pressure Forming Technology for Complex Thin-Walled Components

A new generation of fluid pressure forming technology has been developed for the three typical structures of tubes, sheets, and shells, and hard-to-deform material components that are urgently needed for aerospace, aircraft, automobile, and high-speed train industries. In this paper, an overall review is introduced on the state of the art in fundamentals and processes for lower-pressure hydroforming of tubular components, double-sided pressure hydroforming of sheet components, die-less hydroforming of ellipsoidal shells, and dual hardening hot medium forming of hard-to-deform materials. Particular attention is paid to deformation behavior, stress state adjustment, defect prevention, and typical applications. In addition, future development directions of fluid pressure forming technology are discussed, including hyper lower-loading forming for ultra-large non-uniform components, precision forming for intermetallic compound and high-entropy alloy components, intelligent process and equipment, and precise finite element simulation of inhomogeneous and strong anisotropic thin shells.

Shijian Yuan  

Article  |  2021-03-24

Development of Industrial Internet Security Technology in China

As the new-generation information technology, such as cloud computing and big data, integrates in depth with traditionalindustrial operation technologies, the industrial Internet becomes a new driving force for the digital transformation of industrialenterprises. Meanwhile, industrial Internet security problems have increased; therefore, improving the technological capabilities forguaranteeing industrial Internet security becomes the prerequisite for the high-quality development of the industrial Internet. In thisstudy, we first analyze the demand for industrial Internet development and summarize the development status of industrial Internetsecurity protection, evaluation, and monitoring technologies. Subsequently, we investigate the development trend, technologicaldifficulties, and challenges for the industrial Internet security technology, and propose the key technologies and their developmentapproaches. To promote the safe and healthy development of industrial Internet in China, the industrial Internet security technologiesneed to be customized in accordance with industrial characteristics and scenarios, and closely integrate with new technologies such asbig data and AI, to achieve active defense and create endogenous security capabilities.

Dong Yue ,   Wang Zhiqin   et al.

Article  |  2021-03-23

Construction and Implementation Path for Industrial Internet Standards System in China

Industrial Internet links the new-generation information technology and advanced industries; therefore, industrial Internet standardization is crucial for both the innovative development of the industrial Internet and the effective connection of all links in the industrial chain. In this study, we review the foundation work conducted in China and abroad for the standardization of the industrial Internet in fields such as industrial network, big data, platform, and information security, and summarize the problems faced by industrial Internet standardization. Moreover, a framework of the industrial Internet standards system is proposed, consisting of basic and common, network, data, platform, and security standards. An implementation path for industrial Internet standardization is proposed and demonstrated, focusing on common demand in key areas such as reference architecture construction; interconnectivity in data circulation, processing, and use; monitoring control and decision optimization; and network security. Advancing the industrial Internet standards system requires accelerating breakthroughs for key industrial Internet standards, strengthening the application and promotion of standards, and cultivate and improve the industrial ecology.

Hu Lin ,   Yang Jianjun   et al.

Article  |  2021-03-23

Network Security Management and Protection of Industrial Internet Equipment

The new generation of information and communications technology is deeply integrated with the industrial system. The industrial Internet promotes the ubiquitous and deep interconnection and comprehensive perception of human, machines, and things. The industrial Internet equipment becomes increasingly networked, digital, and intelligent; therefore, the network security design, application management, and protection of these equipment become increasingly important. In this study, we clarify the connotation, protection scope, and requirements of the industrial Internet equipment, and summarize the development status of industrial Internet in China and abroad from the aspects of security control and security certification. Moreover, the problems regarding the network security of industrial Internet equipment in China are analyzed, and the specific implementation paths regarding the network security management and protection for the industrial internet equipment in China are discussed. Furthermore, several development suggestions are proposed. Specifically, the network security access mechanism of the industrial Internet equipment should be improved at the national level, a network security testing and certification system for the equipment should be established, research on the network security architecture and engineering application of the equipment should be promoted, and the network security risk monitoring and perception of the equipment should be strengthened.

Ma Juan ,   Yu Guangchen   et al.

Article  |  2021-03-22

Layout of Foreign Industrial Internet Security Industry and Its Enlightenment to China

The industrial Internet security industry is crucial for the healthy development of industrial Internet. The layout of this industry in developed countries and regions is relatively perfect. To strengthen the manufacturing, cyberspace, and digital sectors, the layout of this industry in China needs to be optimized. This study investigates the development demands for the industrial Internet security industry using literature research and intelligence analysis. Subsequently, the current status of industrial Internet security industry layout in the United States, Germany, the United Kingdom, Japan, and other developed countries is studied from the aspects of policy guidance, enterprise innovation, collaborative development, capital integration, and alliance ecology. Based on this, the international development trend is analyzed. Meanwhile, the current status and challenges faced by China are discussed in terms of policy and standard, technology and product, market space, investment and financing, and regional layout. The study points out that the optimization of China’s industrial Internet security industry layout should draw on the useful experience of other countries and consider China’s development reality. It is suggested that China should maximize the advantages of its system and mechanism to coordinate the development of the security industry; adhere to independent innovation to create an internationally competitive brand; improve the security standards system to actively lead the international rule making; strengthen the policy and financial support for small- and medium-sized enterprises to stimulate their innovation vitality; and build a collaborative development ecology to create an international and domestic dual circulation development pattern. 

Li Yangchun ,   Wang Hailong   et al.

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